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Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.

USMLE Step 2 is open to all medical students and graduates who have successfully passed the USMLE Step 1. The Step 2 exam assesses the candidates' medical knowledge, skills, and understanding of clinical science essential for patient treatment and care, health promotion and disease prevention.

Reference: http://www.usmle.org/step-1/#question-formats

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USMLE USMLE Exam Syllabus Topics:

SectionObjectives
Step 1 - Basic Medical Sciences- Foundations of Disease and Treatment
  • 1. Biochemistry and Molecular Biology
    • 2. Pathology
      • 3. Physiology
        • 4. Behavioral Sciences
          • 5. Microbiology and Immunology
            • 6. Pharmacology
              Step 3 - Clinical Management- Advanced Clinical Practice
              • 1. Patient Management and Diagnosis
                • 2. Health Maintenance
                  • 3. Clinical Case Simulations (CCS)
                    • 4. Biostatistics and Epidemiology
                      • 5. Emergency Medicine
                        Step 2 CK - Clinical Knowledge- Organ Systems and Clinical Medicine
                        • 1. Obstetrics and Gynecology
                          • 2. Pediatrics
                            • 3. Surgery
                              • 4. Internal Medicine
                                • 5. Preventive Medicine and Public Health
                                  • 6. Psychiatry

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